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Journal of Diseases

January 2017, Volume 4, 1, pp 1-7

Development of Periodontitis after Antihelicobacter Therapy in Patients with Ulcer Disease

Shokhsanam Khurramova


Bekhzod Abdullaev

Shokhsanam Khurramova 1

Bekhzod Abdullaev 2

  1. Junior Scientific Researcher, 2nd year student at Tashkent State Dental Institute, Tashkent, Uzbekistan 1

  2. Scientific researcher, 5th year student of GP faculty, Tashkent Medical Academy, Tashkent, Uzbekistan 2

Pages: 1-7

DOI: 10.18488/journal.99/2017.4.1/

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Article History:

Received: 05 November, 2016
Revised: 20 December, 2016
Accepted: 05 January, 2017
Published: 19 January, 2017


Helicobacter pylori infection is associated with the most common diseases of the stomach and duodenum such as peptic ulcer, gastric cancer, and chronic gastritis. Stomach and duodenum are well-conditioned organs for bacteria. Oral cavity is considered a secondary reservoir of H. pylori. The infection responds well to complex antibacterial treatment, but the risk of recurrence and side effects of this treatment is sufficiently high. This article discusses the H.pylori-related pathology of oral cavity and paradentium, and the side effects and tolerability of eradication therapy. The pathways for optimization of the treatment for H. pylori infection with the use of drugs contributing to the restoration of microflora of the gastrointestinal tract and oral cavity are offered.
Contribution/ Originality
All authors contributed equally to this work. This study was one of few studies, which have investigated affecting antimicrobial and anti-ulcerative drugs to the development of periodontitis. Authors declare that there is found relations between pathogenesis of periodontitis and treatment of peptic ulcer disease.  


Periodontitis, Helicobacter pylori, Ulcer disease, Quadrotherapy, Antimicrobial drugs.



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This study received no specific financial support.

Competing Interests:

The authors declare that they have no competing interests.


All authors contributed equally to the conception and design of the study.

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