Helicobacter pylori infection is associated with the most common
diseases of the stomach and duodenum such as peptic ulcer, gastric
cancer, and chronic gastritis. Stomach and duodenum are well-conditioned
organs for bacteria. Oral cavity is considered a secondary reservoir of
H. pylori. The infection responds well to complex antibacterial
treatment, but the risk of recurrence and side effects of this treatment
is sufficiently high. This article discusses the H.pylori-related
pathology of oral cavity and paradentium, and the side effects and
tolerability of eradication therapy. The pathways for optimization of
the treatment for H. pylori infection with the use of drugs contributing
to the restoration of microflora of the gastrointestinal tract and oral
cavity are offered.
All authors contributed equally to this work. This study was one of few
studies, which have investigated affecting antimicrobial and
anti-ulcerative drugs to the development of periodontitis. Authors
declare that there is found relations between pathogenesis of
periodontitis and treatment of peptic ulcer disease.
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This study received no specific financial support.
The authors declare that they have no competing interests.
All authors contributed equally to the conception and design of the study.