Aim:To study lipid profile and leptin levels in non-obese Libyan
children with asthma.. Materials and Methods:70 Libyan children from
Pediatrics Department, Faculty of Medicine, Benghazi University,
Benghazi, Libya were included for the present study (from 2013 to 2014).
Group I formed the normal control group (N: 30 Children) and Group II
is 40 Libyan children with asthma. Their age group varied from 4 to 12
years old. Serum lipid profile and leptin were measured by routine
standard methods. Results and discussion: The Libyan children with
asthma showed an increase in serum total cholesterol, LDL cholesterol,
VLDL cholesterol, HDL cholesterol and triglycerides. Serum Leptin levels
did not show marked changes between the two groups. The presence of
hypercholesterolemia could be a triggering factor for generation of
proinflammatory response in these children. Though leptin levels did not
show marked response further studies may be necessary to study the role
of leptin in obese asthmatic Libyan children.
Contribution/ Originality
This paper tries to bring out the relationship between serum leptin and
lipid levels in non-obese asthmatic Libyan children and relate it to
serum leptin level.
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Funding:
This study received no specific financial support.
Competing Interests:
The authors declare that they have no competing interests.
Acknowledgement:
All authors contributed equally to the conception and design of the study.
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