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Serum Lipid Profile and Leptin Levels in Asthmatic Libyan Children

Pages: 93-98

DOI: 10.18488/journal.9/2016.3.8/

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Article History:

Received: 09 June, 2016
Revised: 01 October, 2016
Accepted: 19 October, 2016
Published: 02 November, 2016


Aim:To study lipid profile and leptin levels in non-obese Libyan children with asthma.. Materials and Methods:70 Libyan children from Pediatrics Department, Faculty of Medicine, Benghazi University, Benghazi, Libya were included for the present study (from 2013 to 2014). Group I formed the normal control group (N: 30 Children) and  Group II is 40  Libyan children with asthma. Their age group varied from 4 to 12 years old. Serum lipid profile and leptin were measured by routine standard methods. Results and discussion: The Libyan children with asthma showed an increase in serum total cholesterol, LDL cholesterol, VLDL cholesterol, HDL cholesterol and triglycerides. Serum Leptin levels did not show marked changes between the two groups. The presence of hypercholesterolemia could be a triggering factor for generation of proinflammatory response in these children. Though leptin levels did not show marked response further studies may be necessary to study the role of leptin in obese asthmatic Libyan children.
Contribution/ Originality
This paper tries to bring out the relationship between serum leptin and lipid levels in non-obese asthmatic Libyan children and relate it to serum leptin level.


Asthma, Lipid profile, Leptin, Proinflammatory response, Libyan children.



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This study received no specific financial support.

Competing Interests:

The authors declare that they have no competing interests.


All authors contributed equally to the conception and design of the study.

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