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Depression in Business: Herbal or Modern Medicine

Lokanathan M.S. Manikam

Lokanathan M.S. Manikam 1

  1. SEGi University, Kuala Lumpur, Malaysia 1

on Google Scholar
on PubMed

Pages: 64-72

DOI: 10.18488/journal.9.2017.44.64.72

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Article History:

Received: 18 January, 2017
Revised: 18 July, 2017
Accepted: 26 July, 2017
Published: 03 August, 2017


The purpose of this study is to investigate the effectiveness of Hypericum for treating tensions in nowadays commonly business chaos. St. John’s Wort and Duloxetine, Cymbalta as both types of medicine are commonly used to treat depression in the business community today. It focused and covered on the possible side effects, chemical compound structure, functionality, background of both medicine. The previous scientific articles, research papers, case studies, patients’ reviews and issues regarding to the practice of these two medicines have been reviewed and taken into account as well. By identifying the previous clinical researches, St. John’s Wort is safe but less effective due to the unclear evidences. Duloxetine could be safe with presence of safety measures and effective with supporting clear evidences. St John’s Wort could only work as alternative medicine for business tensions unless an individual hardly tolerates with Duloxetine. The priority of Duloxetine hence is over St John’s Wort in choosing medicine for depression treatment as Duloxetine could be safe and more effective than St John’s Wort. By looking at various perspective of both type of medicine provided based on supportive evidences, it concluded that Duloxetine was more reliable and effective than St. John’s Wort in treating depression in our modern business community.

Contribution/ Originality
This study makes a comparison between herbal medicine and modern medicine based on the evidences above which also had given rise on personal opinion and thoughts towards the regarding statements and statistics.


Depression, Business, Duloxetine ,Herbal, Medicine.



[1]          S. Harvey, Depression, 16th ed.: Publication of University of Maryland Medical Center, 2013.

[2]          S. D. Ehrlich. Herbal medicine. 2nd Edn., Publication of University of Maryland Medical Center. pp: 31, 2015.

[3]          T. Hrenchir, 10 most-prescribed antidepressant medications, 21st ed.: Oxford University Press, 2015.

[4]          D. McKenna, 10 top best selling botanicals: What they do, taking charge of your health & wellbeing. taking charge of your health & wellbeing vol. 16. University of Minnesota, 2015.

[5]          C. Multum, "Cymbalta uses, dosage, side effects & warnings-," vol. 96, 2015.

[6]          T. R. Norman and O. S. James, Continuation treatment of major depressive disorder: Is there a case for duloxetine? Drug design, development and therapy, 1st ed.: Dove Medical Press, 2010.

[7]          NCCIH, "NCCAM's 5 most searched-for herbs of 2012. NCCIH," vol. 71, p. 62, 2012.

[8]          Health Day, "Taking St. John's wort for depression carries risks: Study-WebMD. No. 258. July 2015," 2015.

[9]          M. S. Lee, M. A. Yong, C. Seockhoon, W. Richard, l. R. Joe, and S. K. Mun, "The effect of initial duloxetine dosing strategy on nausea in Korean patients with major depressive disorder," Psychiatry Investigation, vol. 9, pp. 391-399, 2012.

[10]        C. Nordqvist, St. John's Wort: Uses, side effects, risks. Medical News Today, 4th ed.: MediLexicon, Intl, 2015.

[11]        A. P. Peron, R. G. Mariucci, V. D. A. Igor, D. Elisângela, S. M. Mário, and E. P. V. Veronica, "Evaluation of the cytotoxicity, mutagenicity and anti-mutagenicity of a natural antidepressant, hypericum perforatum L. (St. John’s Wort), on vegetal and animal test systems," BMC Complementary and Alternative Medicine, vol. 16, p. 768, 2013.

[12]        N. A. Qureshi and M. A. B. Abdullah, Mood disorders and complementary and alternative medicine: A literature review. Neuropsychiatric disease and treatment, 3rd ed.: Dove Medical Press, 2013.

[13]        F. Firenzuoli and G. Luigi, Herbal medicine today: Clinical and research issues. Evidence-based complementary and alternative medicine: ECAM, 8th ed. Oxford University Press, 2007.

[14]        M. Ekor, "The growing use of herbal medicines: Issues relating to adverse reactions and challenges in monitoring safety," Frontiers in Pharmacology. Frontiers Media S.A, vol. 24, p. 52, 2014.

[15]        K. Morien, "Safety of St. John's Wort versus antidepressant drugs review. Herb world news online. Herb Research Foundation. No. 74," p. 369, 2003.

[16]        L. McClure, A. Flower, and S. Price, "Scoping the evidence for the effectiveness of herbal medicines, EHTPA. No. 45," pp. 22-23, 2014.

[17]        M. D. Linda, Chris, and E. D. Mary, "Cymbalta," Everyday Health, vol. 18, p. 45, 2014.

[18]        D. J. M. Goldstein, Y. Y. Craig, and D. A. Mark, Duloxetine in the treatment of major depressive disorder: A double-blind clinical trial, 1st ed.: Physicians Postgraduates, Inc, 2002.

[19]        J. M. D. Moser, "St. John's Wort and duloxetine equally effective in mild to moderate depression," DocGuide. ECNP, vol. 24, p. 65, 2009.


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This study received no specific financial support.

Competing Interests:

The author declares that there are no conflicts of interests regarding the publication of this paper.


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