Journal of Diseases

Published by: Asian Medical Journals
Online ISSN: 2410-6550
Print ISSN: 2413-838X
Total Citations: 0
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No. 2

Value of Radiology Modalities in Diagnosing Benign and Malignant Tumours of Breast: An Observational Study

Pages: 34-39
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Value of Radiology Modalities in Diagnosing Benign and Malignant Tumours of Breast: An Observational Study

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DOI: 10.18488/journal.99.2017.42.34.39

Saeed M. Bafaraj

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Saeed M. Bafaraj (2017). Value of Radiology Modalities in Diagnosing Benign and Malignant Tumours of Breast: An Observational Study. Journal of Diseases, 4(2): 34-39. DOI: 10.18488/journal.99.2017.42.34.39
Breast cancer is the most common malignant tumor among women. The objective of this research is to evaluate the specificity, sensitivity, and accuracy of BSGI, DC, and WE-MRI in the diagnosis of breast benign and malignant breast tumors. 228 female patients have participated in this observational research. The age was ranged from 31-68 years (mean age 42.37 8.14 years) with suspicious breast lesions according to physical and imaging examination (mammography and/or ultrasonography). Moreover, women, who have suspected local regional recurrence after resection of malignant breast tumor and who were suspected to have tumor residual following chemotherapy or radiotherapy were also included. All patients underwent breast specific gamma imaging, DW-MRI, and DCE-MRI examination, and the results of breast MRI were compared with the histopathological results that were used as the standard diagnostic method. In this research, 111 women were found to have breast lesion. All breast lesions were undergone histopathological analysis using needle biopsy and/or excisional biopsy. Also, the results of the pathological analysis were correlated and confirmed with ultrasonography and mammography. The pathologic analysis confirmed that 76 (68.5%) of 111 lesions were benign breast lesions and 35 (31.5 %) of 111 were malignant breast lesions. The results proved that BSGI had the best results for the detection of breast lesions (sensitivity 96.7%, specificity 93.6 % and accuracy 94.8%) as compared with DCE-MRI (sensitivity 92.3%, specificity 85.6% and accuracy 88.2%) and diffusion weighted imaging (sensitivity 94.1%, specificity 88.5% and accuracy 91.4%). The research stated that BSGI is the most appropriate diagnostic tool for breast lesions.

Contribution/ Originality
This study documents that Breast Specific Gamma Imaging (BSGI) is the most suitable diagnostic tool for benign and malignant breast tumors. Specifically, the study has contributed in identifying the specificity, sensitivity, and accuracy of BSGI in the diagnosis of breast lesions and tumors.

Prevalence of Prediabetes and the Associated Risk of Kidney Disease in Apparently Healthy Subjects in Nnewi, Anambra State, Nigeria

Pages: 27-33
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Prevalence of Prediabetes and the Associated Risk of Kidney Disease in Apparently Healthy Subjects in Nnewi, Anambra State, Nigeria

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DOI: 10.18488/journal.99.2017.42.27.33

Ozomma O.P , Ogbodo E.C , Analike R.A , Ezeugwunne I.P , Onah C.E , Amah U.K , Ugwu M.C , Obiorah M.O , Oha P.C , Egbe J.U , Meludu S.C

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Ozomma O.P , Ogbodo E.C , Analike R.A , Ezeugwunne I.P , Onah C.E , Amah U.K , Ugwu M.C , Obiorah M.O , Oha P.C , Egbe J.U , Meludu S.C (2017). Prevalence of Prediabetes and the Associated Risk of Kidney Disease in Apparently Healthy Subjects in Nnewi, Anambra State, Nigeria. Journal of Diseases, 4(2): 27-33. DOI: 10.18488/journal.99.2017.42.27.33
This study was designed to investigate the prevalence of prediabetes and the associated risk of kidney disease in Nnewi, Nigeria. A total of 277 apparently healthy subjects (73males and 204 females) who were willing to participate were recruited. Anthropometric indices and blood pressure were measured using standard methods while the demographic data and dietary pattern of subjects were obtained using a well-structured questionnaire.  5mls of blood was collected from eligible subjects (20 prediabetes and 20 non prediabetes ) and dispensed in fluoride oxalate and plain containers for glucose, creatinine (Cr), Urea(Ur), Na+, K+, Cl-, and HCO3- estimation respectively using standard methods. The result showed a prevalence of 7.2% prediabetes in the population. BMI was significantly higher in prediabetes than the control groups (39.45.8 vs 294.4kg/m2; P>0.05). Again, significant increases in the prediabetic values of FBG (117.5416.84 vs 8316.84mg/dl; P>0.05) than the control group were observed. The SBP (128 11.26 vs 1202.2mmHg; P>0.05) and DBP (924.43 vs 605.3mmHg; P>0.05) was also higher in prediabetic groups. Interestingly, result showed  no significant difference between the renal parameters in prediabetes and non prediabetes (p>0.05). The study therefore, suggests that the major determinant for predabetes in the study population may be hypertension and obesity whereas kidney function was not impaired.

Contribution/ Originality
This study documents the Prevalence of Prediabetes and the associated risk of kidney disease in apparently healthy individuals in Nnewi, Anambra State, Nigeria.

Reducing Surgical Site Infection by Placing Subcutaneous Drain in the Obese Patients

Pages: 21-26
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Reducing Surgical Site Infection by Placing Subcutaneous Drain in the Obese Patients

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DOI: 10.18488/journal.99.2017.42.21.26

Dehkhoda S. , N. Arian Pour , R. Roozegar

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Dehkhoda S. , N. Arian Pour , R. Roozegar (2017). Reducing Surgical Site Infection by Placing Subcutaneous Drain in the Obese Patients. Journal of Diseases, 4(2): 21-26. DOI: 10.18488/journal.99.2017.42.21.26
In this study the effect of placing subcutaneous drain in the incision site of obese patients undergoing bariatric surgery, on the rate of incision site infection was evaluated. 200 obese patients of both sexes included in the study on the basis of the inclusion and exclusion criteria. They were divided into two groups on the basis of their accessibility. For patients belonging to group II (study cases), subcutaneous drain was placed at the incision site. Follow up of the patients shows subcutaneous drain placed at the incision site reduces the rate  of  infection up to 2% which is significantly lower than the infection rate among patients for whom drain was not placed (P<.05). In spite of emphasis to use sutures, drains and foreign bodies only with adequate indications to avoid surgical site infection and based on the merits of employing drain in evacuating the collected material to prevent infection, we recommend the use of subcutaneous drains in obese patients as incision infection may lead to longer hospitalization or readmission. As higher treatment expenditures and higher mortality rate are the consequences of infection, every effort to reduce the consequences rates following bariatric surgery in obese patients is valuable and advisable.

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