Preparation and Spectroscopic Studies for New Cu(II), Co(II), Fe(III) and Zr(II) Complexes of Oxytetracycline Drug. In Vitro Antimicrobial Assessment Studies
The 1:1 and 2:1 M ratio metal complexes of new Cu(II), Co(II), Fe(III) and Zr(II) complexes of Oxytetracycline drug were synthesized. The suggested structures of the resulted complexes based on the results of elemental analyses, molar conductivity, infrared, UV–visible spectra, effective magnetic moment were discussed. The infrared spectral data were suggested that oxytetracycline reacts with metal ions as an ionic bidentate ligand through its carboxylate oxygen and the amide carbonyl oxygen. The antibacterial evaluation of the Oxytetracycline drug and their complexes were also performed against some gram positive and negative bacteria as well as fungi.
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