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Comparison of Psychiatric Comorbidity and Quality of Life (QOL) in Persons with Tuberculosis and People Living with HIV in South-South Nigeria

Nkporbu A. K.

,

ANUSIEM O.O.

,

AGOGBUO M. O.

Nkporbu A. K. 1

ANUSIEM O.O. 2
AGOGBUO M. O. 3

  1. Department of Neuropsychiatry, University of Port Harcourt (UPTH), Nigeria 1

  2. Department of Internal Medicine, University of Port Harcourt (UPTH), Nigeria 2

  3. Department of Community Medicine, University of Calabar Teaching Hospital (UCTH), Nigeria 3

Pages: 1-17

DOI: 10.18488/journal.9.2018.51.1.17

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Article History:

Received: 05 April, 2017
Revised: 16 January, 2018
Accepted: 22 January, 2018
Published: 25 January, 2018


Abstract:

BACKGROUND: Tuberculosis and HIV are two chronic infective medical diseases commonly associated with psychiatric co-morbidity, which further affect the quality of life of the sufferers. AIM: The study was to determine and compare the relationship between psychiatric co-morbidity and quality of life in persons with tuberculosis and PLWHIV. METHODOLOGY: Two hundred and thirty subjects living with HIV and 140 subjects with tuberculosis were recruited. Those with clinically chronic conditions, or comorbid medical condition and treatment Resistant tuberculosis were excluded. Subjects were further administered with the study’s instruments including the socio-demographic questionnaire, GHQ-12, the brief version of the WHO Quality of Life instrument (WHOQOL-Bref) and WHO Composite International Diagnostic Interview (WHO CIDI). Results were presented via descriptive and analytical methods. RESULTS: The study found a prevalence of psychiatric co-morbidity of 19.8% among PLWHIV and 28.4% among subjects with tuberculosis (p = 0.004). For the PLWHIV, domain scores for quality of life were as follows; 60.71±15.57, 62.34±26.32, 61.57±25.04, 55.15±14.00 and 65.81±21.84 while tuberculosis was 50.97±13.87, 57.22±46.36, 54.51±45.04, 50.01±15.10 and 49.34±21.84 (p = 0.001) for physical, psychological, social relationship, environment domains and general health facet respectively. Furthermore, presence of psychiatric comorbidity significantly inversely correlated with quality of life among persons with both medical diseases. CONCLUSION: The study found a statistically significant higher prevalence of psychiatric co-morbidity and lower quality of life among the subjects with tuberculosis compared with PLWHIV. Findings suggest strongly that in managing patients with these conditions, attention should be paid to their mental health and subjective quality of life.
Contribution/ Originality
This study contributes in the existing literature about the sufferers of chronic infectious medical diseases and their vulnerability to psychiatric co-morbidity. The study documents explanations as to why some chronic medical conditions may show slow response to instituted management. The study uses new estimation methodology of Quality of life measurement and demonstrates the direct relationship between psychiatric co-morbidity and quality of life. Finally, the study contributes to logical analysis and emphasis that evaluation of patients suffering from chronic medical diseases must be holistic enough to include their mental wellbeing.

Keywords:

Comparison, Psychiatric comorbidity, QOL, Tuberculosis, PLWHIV, South-South Nigeria.

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