@Article{pakinsight,
AUTHOR = {},
TITLE = {Occurrence and Anti-Fungal Sensitivity Testing of Candida Species Isolated from Canine Conjunctivitis},
JOURNAL = {International Journal of Veterinary Sciences Research},
VOLUME = {2},
YEAR = {2016},
NUMBER = {2},
PAGES = {8-14},
URL = {http://www.pakinsight.com/archive/110/06-2016/2},
ISSN = {2410-9444},
ABSTRACT = {Fungal infection in dogs and other domestic pets caused by Candida 
species have been previously reported. Several available antifungal 
drugs for treatment of yeast associated infections have been used with 
diverse effects. This study establishes antifungal susceptibility 
profile on identified Candida species isolates associated with canine 
conjunctivitis using disks diffusion method as described by NCCLS 
(M44-A). The antifungal disks used include Amphotericin-B (20mcg), 
Nystatin (100units), Itraconazole (10mcg), Ketaconazole (10mcg), 
Fluconazole (25mcg). The identified Candida species were C. albicans, C.
 krusei, C. tropicalis and C. parapsilosis. Percentage susceptibility 
was high in both Amphotericin B (77.27%) and Nystatin (58.18%), while 
Itraconazole showed (54.54%), Ketoconazole (55.45%) and Fluconazole was 
least (11.82%). The sensitivity ranking showed Amphothericin B > 
Nystatin > Itraconazole > Ketoconazole > Fluconazole and 
increased resistance amongst the Azoles especially Fluconazole (70.90%) 
in comparison with Polyenes. C. albicans showed the highest resistance 
(84.51%) to both Fluconazole and ketoconazole (67.61%). C. parapsilosis 
showed 63.64% and 61.54% percentage resistance to Nystatin and 
Itraconazole respectively. In conclusion, this finding showed that 
Amphotericin B and Nystatin were most effective against isolated Candida
 species. Proper diagnosis of the underlying ailment is necessary in 
conjunction with routine anti-fungal susceptibility testing to avoid 
drug abuse and resistance.},
DOI = {10.18488/journal.110/2016.2.2/110.2.8.14}
}