International Journal of Medical and Health Sciences Research

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No. 1

Difficulties in Thought, Language and Communication: A Cross-Sectional Study of Psychiatric People in Bangladesh

Pages: 36-42
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Difficulties in Thought, Language and Communication: A Cross-Sectional Study of Psychiatric People in Bangladesh

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DOI: 10.18488/journal.9.2021.81.36.42

Mizanur Rahman , H.M. Abubakar Siddik , Md Zobaer Hasan , Jannatul Ferdous , Masud Alam , Md. Saiful Islam , Md. Fakhrul Islam

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Mizanur Rahman , H.M. Abubakar Siddik , Md Zobaer Hasan , Jannatul Ferdous , Masud Alam , Md. Saiful Islam , Md. Fakhrul Islam (2021). Difficulties in Thought, Language and Communication: A Cross-Sectional Study of Psychiatric People in Bangladesh. International Journal of Medical and Health Sciences Research, 8(1): 36-42. DOI: 10.18488/journal.9.2021.81.36.42
People with Psychiatric disorder (PD) have difficulties in their thought, language and communication skills. In Bangladesh, the frequency of mental disorders is 12.2%, where females are more vulnerable than the male. The main purpose of this study was to find out the thought, language and communication aspects among psychiatric population in Bangladesh. A cross-sectional survey was conducted to meet the study aim, and the data from 70 participants with different types of psychiatric disorder were collected from a specialized mental health hospital in Bangladesh. The participants were between 18 to 65 years old, where the ratio of the male and female was almost equal. A significant (p-value=0.006) relationship was found between language disorder (incoherence) and different types of psychiatric disorder. Professionals, working with psychiatric population need to remain alert to the presence of those issues and refer to appropriate specialists that will increase the wellbeing quality of people with Psychiatric disorder (PD) as well as decrease morbidity.
Contribution/ Originality
This study is one of very few studies which have investigated the thought, language and communication aspects among psychiatric population in Bangladesh and significant relationship was found between language disorder (incoherence) and different types of psychiatric disorder.

A Scientometric Analysis of Highly Cited Publications and a Summary of Top 25 Articles Regarding Covid-19

Pages: 24-35
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A Scientometric Analysis of Highly Cited Publications and a Summary of Top 25 Articles Regarding Covid-19

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DOI: 10.18488/journal.9.2021.81.24.35

Ali Kemal Erenler , Mehmet Oguzhan Ay , Ahmet BAYDIN

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Ali Kemal Erenler , Mehmet Oguzhan Ay , Ahmet BAYDIN (2021). A Scientometric Analysis of Highly Cited Publications and a Summary of Top 25 Articles Regarding Covid-19. International Journal of Medical and Health Sciences Research, 8(1): 24-35. DOI: 10.18488/journal.9.2021.81.24.35
Scientometric analyses allow to shed light to status of the current literature and provide guidance to future studies. We aimed to analyze highly cited articles in terms of study fields, authors, organizations and countries. We also summarized top 25 articles for future perspectives. The Web of Science database which allows statistical analysis of a specific subject was used for data collection. We obtained highly cited publications (cited ?6 times) and investigated them in terms of categories, countries, authors, organizations, languages, countries and journals. We also analyzed top 25 articles from full-texts and summarized them. Majority of the highly cited articles were about General Internal Medicine. Huazhong University of Science Technology was on the top of the list followed by Harvard University. Majority of the highly cited articles were published by authors from China. Journal of Medical Virology was the leading journal followed by Science of the Total Environment. English was the most common language used in articles. Clinical characteristics, diagnostic tools and treatment methods were the popular study fields when top 25 articles were considered. Scientometric analysis of the highly cited publications revealed that China, as the origin of the pandemic, was the leading country in terms of citations. Publishers and authors should be aware of inconveniences caused by rapid publication.
Contribution/ Originality
This is also the unique study to summarize the top 25 articles on COVID-19 to guide future studies in this field.

The Association between Long Term Alcohol Consumption and Dementia

Pages: 13-23
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The Association between Long Term Alcohol Consumption and Dementia

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DOI: 10.18488/journal.9.2021.81.13.23

Baozhen Dai , Joseph Marfoh

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Baozhen Dai , Joseph Marfoh (2021). The Association between Long Term Alcohol Consumption and Dementia. International Journal of Medical and Health Sciences Research, 8(1): 13-23. DOI: 10.18488/journal.9.2021.81.13.23
The study assessed the association between long-term alcohol consumption and risk of dementia in a panel study of 177 countries from 2000 to 2009. The study used econometric techniques to analyze the association between long-term alcohol consumption and risk of dementia. However, it employed the ordinary least square regression method and the fully modified ordinary least square regression method for robust inference. The study found that alcohol consumption is heterogeneously associated with dementia regarding the associated risk factors such as alcoholic disorder, anxiety disorder, depression disorder, bipolar disorder, and Schizophrenia. Moreover, some contributing factors such as age, eating disorder, smoking, and educational level play a significant role in attributing to dementia with the risk factor. However, it is recommended that alcohol consumption be reasonably taken to avoid its consequences. More specifically, ethanol is neurotoxic, crosses the blood-brain barrier to enter neurons directly, and can cause pathological processes leading to brain damage in high concentrations and its metabolite acetaldehyde.
Contribution/ Originality
This study uses an econometric methodology to assess the association between long-term alcohol consumption and risk of dementia in a panel study. The study found that alcohol consumption is heterogeneously associated with dementia regarding the associated risk factors such as alcoholic disorder, anxiety disorder, depression disorder, bipolar disorder, and Schizophrenia.

A Woman in Her Forties with Six Months of Worsening Dyspnea

Pages: 8-12
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A Woman in Her Forties with Six Months of Worsening Dyspnea

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DOI: 10.18488/journal.9.2021.81.8.12

Dilpat Kumar , Minh HN Nguyen , Simran S Kenth , FNU Warsha

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Dilpat Kumar , Minh HN Nguyen , Simran S Kenth , FNU Warsha (2021). A Woman in Her Forties with Six Months of Worsening Dyspnea. International Journal of Medical and Health Sciences Research, 8(1): 8-12. DOI: 10.18488/journal.9.2021.81.8.12
Uterine leiomyosarcoma (ULMS) is a rare cancer that originates from the smooth muscle of the uterine wall. ULMS is aggressive with a high rate of recurrence and mortality. Although the majority of ULMS are initially diagnosed within the uterus, they possess a high metastatic potential. Two thirds of metastatic ULMS sites involve the lung. However, the clinical presentations of such metastases are surprisingly not well described. In this case, we describe a case of a woman in her forties who presented with 6 months of worsening dyspnea and chronic cough. Her pulmonary function test demonstrated severe restrictive lung disease. Computed tomography (CT) of the chest was done which showed multiple pulmonary nodules. CT abdomen and pelvis identified multiple uterine masses with largest being 17 cm. Biopsy of uterine masses confirmed the diagnosis of UMLS. Her restrictive lung disease was diagnosed to be secondary to UMLS, as patient had no other identifiable risk factors.
Contribution/ Originality
This paper documents a rare case of uterine leiomyosarcoma (ULMS) that presented as severe restrictive lung disease. It further highlights the essence of keeping broad differentials when managing a patient with non-specific pulmonary symptoms.

Effect of Quercetin on Liver Oxidative Stress Parameters Induced by Butylparaben in Male Wistar Rats

Pages: 1-7
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Effect of Quercetin on Liver Oxidative Stress Parameters Induced by Butylparaben in Male Wistar Rats

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DOI: 10.18488/journal.9.2021.81.1.7

Adebayo Olugbenga Adegoke , Rex Njoku , Olugbenga Emmanuel Bamigbowu , Utibeabasi Idem Idung

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Adebayo Olugbenga Adegoke , Rex Njoku , Olugbenga Emmanuel Bamigbowu , Utibeabasi Idem Idung (2021). Effect of Quercetin on Liver Oxidative Stress Parameters Induced by Butylparaben in Male Wistar Rats. International Journal of Medical and Health Sciences Research, 8(1): 1-7. DOI: 10.18488/journal.9.2021.81.1.7
Parabens are hormonally active chemicals widely used as preservatives in foods, cosmetics, toiletries and pharmaceuticals. Quercetin is a flavonoid with antioxidant property found in many fruits, plants and vegetables. The study investigated the effect of quercetin on the liver oxidative stress parameters induced by butylparaben in wistar rats. Thirty albino rats divided into six (6) groups of five rats were administered with 100mg/kg of butylparaben (BP), 100mg/kg of BP and 25mg/kg of quercetin (Q), 100mg/kg of BP and 50mg/kg of Q, 100mg/kg of BP and 100mg/kg of Q, 100mg/kg of BP and 200mg/kg of Q all dissolved in corn while the control were fed rat diet and water ad libitum with corn oil three (3) times weekly for sixty (60) days. The rats were sacrificed and liver harvested, homogenized and used for malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD) and glutathione peroxidase (GPx) estimation using thiobarbituric acid method, Ellman’s method, epinephrine method and Rotruck et al method respectively while biuret and bromocresol green methods were used to estimate the blood Total protein and albumin levels respectively. The result showed significant difference(p<0.005) in concentrations of MDA (µmol MDA/mg protein) (2.62±0.44, 7.65±0.50 and 3.21±1.14), GSH (Units/mg protein) (12.65±1.52, 6.50±1.70, and 14.58±3.05), SOD (Units/mg protein) (90.67±8.30, 62.67±4.35 and 81.04±8.41),GPx (Units/mg protein) (1.16±2.81, 1.05±0.56 and 1.17±0.55), Total protein (g/L) (58.41±2.10, 55.08±3.60 and 58.41±2.10) and Albumin (g/L) (45.20±1.05, 40.69±4.82 and 42.14±1.51) for Control, (Bp) and (Bp+Q) respectively. The result has shown that quercetin caused a reversal of butylparaben-induced toxicity on liver oxidative stress parameters.
Contribution/ Originality
The study investigated the effect of quercetin on the liver oxidative stress parameters induced by butylparaben in wistar rats.