Besalat Hussain , Fatima Mushtaq , Naima Javed , Affa Khan (2018). An Observational Study Evaluating the Impact of Chikungunya Virus Infection on Oral Cavity and Temporomandibular Joint. International Journal of Medical and Health Sciences Research, 5(1): 18-24. DOI: 10.18488/journal.9.2018.51.18.24
Over a past few years, a very limited number of studies researched whether the chikungunya virus affects the oral cavity in addition to pronounced symptoms in extremities but on literature review different studies were found to have different conclusions. Thus an Observational Study was conducted evaluating the impact of Chikungunya Virus Infection on Oral Cavity and Temporomandibular Joint. This was a cross sectional study having a self-designed questionnaire, descriptive and associative tests were run for Data analysis using SPSS. Out of 527 tested, 204 patients were found seropositive and 135 were selected for data analysis on their consent (N 135). Pain and burning sensation of mouth (71.1%), discomfort in mouth opening (65.9%), Bleeding gums (53.3%), and taste aversion (50.3%) were the most common complaints followed by Inability to chew food (48.1%), Discomfort in swallowing (35.5%), Halitosis (34.8%) and tenderness over TMJ (30.4%). The study significantly recorded pain, discomfort and bleeding gums intraorally. Pain, tenderness and decreased efficiency of temporomandibular joint were also noted.
This study contributes in the existing literature of Chikungunya virus infection. Interval estimation statistical method is used. It is one of very few studies which have investigated impact of Chikungunya Virus Infection on Oral Cavity and Temporomandibular Joint and concluded it to be quite painful and uncomfortable to bear causing burning gums, limiting speech, decreased chewing ability, altering taste perception, TM-joint and muscles tenderness and difficulty in food swallowing.
Comparison of Psychiatric Comorbidity and Quality of Life (QOL) in Persons with Tuberculosis and People Living with HIV in South-South Nigeria
Nkporbu A. K. , ANUSIEM O.O. , AGOGBUO M. O. (2018). Comparison of Psychiatric Comorbidity and Quality of Life (QOL) in Persons with Tuberculosis and People Living with HIV in South-South Nigeria. International Journal of Medical and Health Sciences Research, 5(1): 1-17. DOI: 10.18488/journal.9.2018.51.1.17
BACKGROUND: Tuberculosis and HIV are two chronic infective medical diseases commonly associated with psychiatric co-morbidity, which further affect the quality of life of the sufferers. AIM: The study was to determine and compare the relationship between psychiatric co-morbidity and quality of life in persons with tuberculosis and PLWHIV. METHODOLOGY: Two hundred and thirty subjects living with HIV and 140 subjects with tuberculosis were recruited. Those with clinically chronic conditions, or comorbid medical condition and treatment Resistant tuberculosis were excluded. Subjects were further administered with the study’s instruments including the socio-demographic questionnaire, GHQ-12, the brief version of the WHO Quality of Life instrument (WHOQOL-Bref) and WHO Composite International Diagnostic Interview (WHO CIDI). Results were presented via descriptive and analytical methods. RESULTS: The study found a prevalence of psychiatric co-morbidity of 19.8% among PLWHIV and 28.4% among subjects with tuberculosis (p = 0.004). For the PLWHIV, domain scores for quality of life were as follows; 60.71±15.57, 62.34±26.32, 61.57±25.04, 55.15±14.00 and 65.81±21.84 while tuberculosis was 50.97±13.87, 57.22±46.36, 54.51±45.04, 50.01±15.10 and 49.34±21.84 (p = 0.001) for physical, psychological, social relationship, environment domains and general health facet respectively. Furthermore, presence of psychiatric comorbidity significantly inversely correlated with quality of life among persons with both medical diseases. CONCLUSION: The study found a statistically significant higher prevalence of psychiatric co-morbidity and lower quality of life among the subjects with tuberculosis compared with PLWHIV. Findings suggest strongly that in managing patients with these conditions, attention should be paid to their mental health and subjective quality of life.
This study contributes in the existing literature about the sufferers of chronic infectious medical diseases and their vulnerability to psychiatric co-morbidity. The study documents explanations as to why some chronic medical conditions may show slow response to instituted management. The study uses new estimation methodology of Quality of life measurement and demonstrates the direct relationship between psychiatric co-morbidity and quality of life. Finally, the study contributes to logical analysis and emphasis that evaluation of patients suffering from chronic medical diseases must be holistic enough to include their mental wellbeing.